Common trade name: Prednisone/prednisolone has no common trade name and is available as a generic drug. Methylprednisolone may be known as Medrol, Depo-Medrol, or Solu-Medrol. Dexamethasone may be known as Azium or Dexasone.
Drug class: Glucocorticoid
Indicated for: Inflammatory conditions including atopic dermatitis, flea allergy dermatitis, hives, insect bite hypersensitivity, and allergic rhinitis and bronchitis. Also used for many other conditions, including hypoadrenocorticism (Addison’s disease), immune-mediated diseases (such as immune-mediated hemolytic anemia), and cancer (such as lymphoma).
Contraindications: Should not be used in dogs with systemic fungal infections, viral infections, hyperadrenocorticism (Cushing’s disease), corneal ulcers, or gastrointestinal ulcers. Should be used with caution in dogs with congestive heart failure, high blood pressure (hypertension), liver disease, or kidney disease.
Potential side effects: Increased thirst, hunger, and urination. May also cause panting and lethargy. See sidebar for potential long-term side effects.
Formulations available: Prednisone and prednisolone are available as tablets and oral syrups/solutions. Many oral syrups/solutions contain alcohol and should be avoided in dogs. Methylprednisolone is available as tablets and as an injection for veterinary use only. Dexamethasone is available as tablets, oral solution, and as an injection for veterinary use only. All formulations require a prescription.
